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omero-integration

The omero-integration skill provides programmatic access to OMERO, an open-source microscopy data management platform. Use this skill when working with the OMERO Python API to retrieve microscopy images and datasets, analyze pixel data, manage regions of interest and annotations, perform batch processing, or conduct high-content screening analysis workflows. It covers connection management, hierarchical data navigation, metadata annotation, pixel processing, and server-side scripting capabilities for research imaging applications.

Install in Claude Code
Copy
git clone --depth 1 https://github.com/K-Dense-AI/scientific-agent-skills /tmp/omero-integration && cp -r /tmp/omero-integration/skills/omero-integration ~/.claude/skills/omero-integration
Then start a new Claude Code session; the skill loads automatically.

SKILL.md

# OMERO Integration

Use current OME documentation and the smallest explicit data scope. OMERO data
may contain unpublished images, identifiers, annotations, original files, and
derived measurements.

## Verified Baseline

This skill was refreshed on **2026-07-23**:

- **OMERO.server 5.6.18** (May 2026) is the current documented stable server.
- It was tested by OME with **OMERO.py/omero-py 5.22.1** and
  **OMERO.web 5.31.0**.
- `omero-py==5.22.1` requires Python 3.10 or newer. The OMERO support matrix
  supports 3.10 and 3.11, recommends 3.12, and still labels 3.13/3.14
  “upcoming.”
- OMERO 5.6 uses **IcePy 3.6**, with 3.6.5 prebuilt client wheels documented
  for Python versions through 3.12.

The pin above is a reproducible skill snapshot, not a promise that every
OMERO.server release accepts that client. For another server version, consult
its release entry and use the OMERO.py version tested with it. See
[`references/sources.md`](references/sources.md).

## Operating Contract

1. Start with local validation or a dry run. Do not connect until the user has
   selected the host, group, object type, IDs, and result limit.
2. Read credentials only from the named `OMERO_*` variables in the frontmatter.
   Never search parent directories or load `.env` files.
3. Never place a password or session key in command arguments, source code,
   output JSON, logs, tracebacks, or chat. A session key is a bearer credential.
4. Default to `secure=True`. OMERO encrypts login by default, but post-login
   data and the session ID may otherwise travel unencrypted. `secure=True` does
   not by itself guarantee certificate hostname verification.
5. Bound every list, page, ROI, shape, annotation, table row, pixel plane, and
   local file scan. Do not turn an object request into a group-wide or
   cross-group export without explicit approval.
6. Treat all writes separately: annotation/link creation, rendering-default
   saves, image creation, imports, script uploads, table writes, ownership or
   group changes, and deletion require an exact reviewed target.
7. Close `BlitzGateway`, table handles, raw stores, thumbnail stores, rendering
   engines, script clients, and other stateful services in `finally` blocks or
   documented context-manager patterns.
8. Never connect to a real server merely to “test” examples.

## Choose the Interface

- **BlitzGateway (`omero-py`)**: primary Python client for object traversal,
  pixels, annotations, ROIs, rendering, and services.
- **OMERO CLI**: sessions, import scanning/import, OME-TIFF or XML export,
  scripts, and administrative plugins. Most client commands are remote; import
  also needs the matching server-side Java libraries through `OMERODIR`.
- **OMERO.web `api` and `webgateway`**: the only OMERO.web apps that official
  documentation calls stable public APIs. The documented JSON API is
  version-discovered and has limited object coverage; it is not evidence that
  every webclient URL is a supported REST endpoint.
- **OMERO.server scripts**: uploaded plugins executed by server infrastructure.
  They are different from the bundled local client helpers in `scripts/`.

## Install a Reproducible Client

Create a Python 3.12 environment:

```bash
uv venv --python 3.12 .venv
source .venv/bin/activate
```

Install the exact IcePy 3.6.5 wheel matching the interpreter, OS, architecture,
and wheel tags, then OMERO.py:

```bash
# Download the matching 3.6.5 wheel from the official OMERO-linked matrix.
uv pip install "/absolute/path/to/zeroc_ice-3.6.5-<matching-tags>.whl"
uv pip install "omero-py==5.22.1"
```

Do not substitute Ice 3.7: the OMERO 5.6 support matrix marks Ice 3.6 as
recommended and 3.7 as unsupported. A plain install may attempt to compile
IcePy from source; prefer a reviewed matching wheel. The upstream package is
GPL-2.0-or-later; this skill’s own files are MIT.

For import/admin commands only, `OMERODIR` must point to a compatible extracted
OMERO.server directory. A normal remote BlitzGateway client does not require
that server tree. Read [`references/connection.md`](references/connection.md)
before installation or authentication work.

## Credentials and Connection

Set named variables in the calling environment or secret manager. Do not put
the password on an `omero` CLI command:

```bash
export OMERO_HOST="omero.example.org"
export OMERO_PORT="4064"
export OMERO_USER="researcher"
export OMERO_SECURE="true"
# Supply OMERO_PASSWORD through the environment/secret manager, or use
# OMERO_SESSION_KEY as an alternative. Do not echo either value.
```

A password-authenticated, exception-safe read pattern is:

```python
import os
from omero.gateway import BlitzGateway

conn = None
try:
    conn = BlitzGateway(
        os.environ["OMERO_USER"],
        os.environ["OMERO_PASSWORD"],
        host=os.environ["OMERO_HOST"],
        port=int(os.environ.get("OMERO_PORT", "4064")),
        secure=True,
    )
    if not conn.connect():
        raise RuntimeError("OMERO connection failed")

    images = conn.getObjects(
        "Image",
        opts={"limit": 25, "offset": 0, "order_by": "obj.id"},
    )
    for image in images:
        print(image.getId())  # Do not print names unless requested.
finally:
    if conn is not None:
        conn.close()
```

For existing-session and CLI prompt patterns, certificate verification,
group context, and cleanup details, read
[`references/connection.md`](references/connection.md).

## Bundled Safe Helpers

All helpers use `argparse`; `--help` works without OMERO installed. Remote
helpers are dry-run by default and require `--execute`.

```bash
python -B scripts/validate_config.py --help
python -B scripts/inventory.py --help
python -B scripts/export_image_metadata.py --help
python -B scripts/plan_transfer.py --help
```

- `validate_config.py`: validates only named endpoint/auth variables locally;
  optional DNS resolution still does not contact OMERO.
- `inventory.py`: bounded, read-only object inventory with paged JSON output.
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