Skills de Claude Code · página 117

Query ChEMBL's bioactive molecules and drug discovery data. Search compounds by structure/properties, retrieve bioactivity data (IC50, Ki), find inhibitors, perform SAR studies, for medicinal chemistry.

Christian mystical wisdom through Aramaic lens - Kingdom within, Christ consciousness, feminine divine, embodiment navigation

Open-source embedding database for AI applications. Store embeddings and metadata, perform vector and full-text search, filter by metadata. Simple 4-function API. Scales from notebooks to production clusters. Use for semantic search, RAG applications, or document retrieval. Best for local development and open-source projects.

Browser automation, debugging, and performance analysis using Puppeteer CLI scripts. Use for automating browsers, taking screenshots, analyzing performance, monitoring network traffic, web scraping, form automation, and JavaScript debugging.

Quantum computing framework for building, simulating, optimizing, and executing quantum circuits. Use this skill when working with quantum algorithms, quantum circuit design, quantum simulation (noiseless or noisy), running on quantum hardware (Google, IonQ, AQT, Pasqal), circuit optimization and compilation, noise modeling and characterization, or quantum experiments and benchmarking (VQE, QAOA, QPE, randomized benchmarking).

Analyzes Claude Code usage patterns and provides comprehensive recommendations. Runs usage analysis, discovers GitHub community resources, suggests CLAUDE.md improvements, and fetches latest docs on-demand. Use when user wants to optimize their Claude Code workflow, create configurations (agents/skills/commands), or set up project documentation.

Migrate prompts and code from Claude Sonnet 4.0, Sonnet 4.5, or Opus 4.1 to Opus 4.5. Use when the user wants to update their codebase, prompts, or API calls to use Opus 4.5. Handles model string updates and prompt adjustments for known Opus 4.5 behavioral differences. Does NOT migrate Haiku 4.5.

Comprehensive collection of 128+ ready-to-use scientific skills for Claude enabling research across biology, chemistry, medicine, genomics, and advanced analysis domains.

把旅行行程做成美观、离线可读、手机优先的单文件 HTML（交互地图+每日时间轴+出发前订票提醒）。两种用法——只给目的地和天数让它帮你规划，或丢一份现成计划让它直接出页面。触发：旅行计划可视化、做旅行攻略网页、行程 HTML、travel plan visualization。

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Activate ATLAS pattern recognition mode. Identify repeated patterns, extract essential characteristics, and create reusable abstractions from concrete examples.

Adversarially review something just built — presume it is broken and find where. Use after implementing a feature, finishing a build, or before shipping, or whenever ATLAS or Boss wants a hostile second opinion on a diff, a running app, or a whole codebase. Spawns clean-context reviewers with opposing lenses (correctness, security, empty-world) and reproduces every finding by running the target before believing it. Distinct from /code-review, which statically reads a diff and never runs the app.

Creating algorithmic art using p5.js with seeded randomness and interactive parameter exploration. Use this when users request creating art using code, generative art, algorithmic art, flow fields, or particle systems. Create original algorithmic art rather than copying existing artists' work to avoid copyright violations.

Stop and consult this skill whenever your response would include specific facts about Anthropic's products. Covers: Claude Code (how to install, Node.js requirements, platform/OS support, MCP server integration, configuration), Claude API (function calling/tool use, batch processing, SDK usage, rate limits, pricing, models, streaming), and Claude.ai (Pro vs Team vs Enterprise plans, feature limits). Trigger this even for coding tasks that use the Anthropic SDK, content creation mentioning Claude capabilities or pricing, or LLM provider comparisons. Any time you would otherwise rely on memory for Anthropic product details, verify here instead — your training data may be outdated or wrong.

Create beautiful visual art in .png and .pdf documents using design philosophy. You should use this skill when the user asks to create a poster, piece of art, design, or other static piece. Create original visual designs, never copying existing artists' work to avoid copyright violations.

Index of official Claude Code / Anthropic docs — fetches the right page on demand

Use this skill whenever the user wants to create, read, edit, or manipulate Word documents (.docx files). Triggers include: any mention of 'Word doc', 'word document', '.docx', or requests to produce professional documents with formatting like tables of contents, headings, page numbers, or letterheads. Also use when extracting or reorganizing content from .docx files, inserting or replacing images in documents, performing find-and-replace in Word files, working with tracked changes or comments, or converting content into a polished Word document. If the user asks for a 'report', 'memo', 'letter', 'template', or similar deliverable as a Word or .docx file, use this skill. Do NOT use for PDFs, spreadsheets, Google Docs, or general coding tasks unrelated to document generation.

Helps users discover and install agent skills when they ask questions like "how do I do X", "find a skill for X", "is there a skill that can...", or express interest in extending capabilities. This skill should be used when the user is looking for functionality that might exist as an installable skill.

Deliberate-choice procedure for a medium-to-high-stakes engineering fork — when the first plausible solution (the instinct, the default next-token pull) would be costly to get wrong. Fires AUTONOMOUSLY: invoke proactively whenever a fork fits, never wait to be asked — mechanical triggers include a fix failing for the 2nd-3rd time, adding a dependency, schema/migration design, deleting or deprecating things others depend on, changing a public API, choosing an architecture or stack. Refuse the premature collapse: hold real options open (urge · contrarian · synthesis · out-of-box · intuitive dots · precedent · first-principles), ground each branch in at least one fact from outside the model (codebase, docs, benchmark, spike), future-model consequences (blast radius, reversibility, maintenance, pre-mortem), collapse by deliberate choice, then try to refute the winner before acting. Log the decision and rejected branches in docs/decision_logs/. Not for routine calls — a decision worth more than one forward pass.

Create distinctive, production-grade frontend interfaces with high design quality. Use this skill when the user asks to build web components, pages, artifacts, posters, or applications (examples include websites, landing pages, dashboards, React components, HTML/CSS layouts, or when styling/beautifying any web UI). Generates creative, polished code and UI design that avoids generic AI aesthetics.

Write content in any language indistinguishable from a skilled human writer. Avoids AI-sounding phrases, varies sentence structure, creates natural prose. Detects target language and loads language-specific AI-tells, register, and orthography from `languages/`.

Record a hard-won engineering lesson after a bug or mistake is resolved. Use when a bug resisted ATLAS until Boss's guidance cracked it, or when a long debugging hunt ended in an aha moment worth never relearning.

Guide for creating high-quality MCP (Model Context Protocol) servers that enable LLMs to interact with external services through well-designed tools. Use when building MCP servers to integrate external APIs or services, whether in Python (FastMCP) or Node/TypeScript (MCP SDK).

Use this skill whenever the user wants to do anything with PDF files. This includes reading or extracting text/tables from PDFs, combining or merging multiple PDFs into one, splitting PDFs apart, rotating pages, adding watermarks, creating new PDFs, filling PDF forms, encrypting/decrypting PDFs, extracting images, and OCR on scanned PDFs to make them searchable. If the user mentions a .pdf file or asks to produce one, use this skill.

Automate browser interactions, test web pages and work with Playwright tests.

PostgreSQL-specific code review assistant focusing on PostgreSQL best practices, anti-patterns, and unique quality standards. Covers JSONB operations, array usage, custom types, schema design, function optimization, and PostgreSQL-exclusive security features like Row Level Security (RLS).

PostgreSQL-specific development assistant focusing on unique PostgreSQL features, advanced data types, and PostgreSQL-exclusive capabilities. Covers JSONB operations, array types, custom types, range/geometric types, full-text search, window functions, and PostgreSQL extensions ecosystem.

Use this skill any time a .pptx file is involved in any way — as input, output, or both. This includes: creating slide decks, pitch decks, or presentations; reading, parsing, or extracting text from any .pptx file (even if the extracted content will be used elsewhere, like in an email or summary); editing, modifying, or updating existing presentations; combining or splitting slide files; working with templates, layouts, speaker notes, or comments. Trigger whenever the user mentions \"deck,\" \"slides,\" \"presentation,\" or references a .pptx filename, regardless of what they plan to do with the content afterward. If a .pptx file needs to be opened, created, or touched, use this skill.

Manages shadcn components and projects — adding, searching, fixing, debugging, styling, and composing UI. Provides project context, component docs, and usage examples. Applies when working with shadcn/ui, component registries, presets, --preset codes, or any project with a components.json file. Also triggers for "shadcn init", "create an app with --preset", or "switch to --preset".

Create new skills, modify and improve existing skills, and measure skill performance. Use when users want to create a skill from scratch, edit, or optimize an existing skill, run evals to test a skill, benchmark skill performance with variance analysis, or optimize a skill's description for better triggering accuracy.

Postgres performance optimization and best practices from Supabase. Use this skill when writing, reviewing, or optimizing Postgres queries, schema designs, or database configurations.

Complete Product Owner / Product Manager capability — a wiki-style knowledge map of product practice in active software development: the role and its boundaries, strategy cascade (vision → OKRs → roadmap → backlog), continuous discovery, backlog craft (epics, INVEST stories, acceptance criteria), prioritization frameworks (RICE, MoSCoW, Kano, WSJF), sprint delivery, metrics (North Star, AARRR), stakeholder management, and anti-patterns. The PO/PM owns what gets built, in what order, and why — including the end-to-end user flows and user journeys. Use when scoping a product or feature, decomposing an idea into outcomes/epics/stories, prioritizing a backlog, defining an MVP, mapping user journeys, measuring success, or saying no to a stakeholder. Pairs with super-ui-ux-design, which owns how each screen looks and behaves.

Complete UI/UX design capability — a wiki-style knowledge map of design theory (UX laws, Nielsen heuristics, usability, visual hierarchy, typography, contrast/WCAG, design systems, aesthetics-vs-conversion) fused with a hands-on execution playbook for building distinctive, production-grade frontend interfaces. Use when designing or building any UI (websites, landing pages, dashboards, components, apps), reviewing or critiquing UI/UX, diagnosing why a design doesn't convert, or styling/beautifying web interfaces. Grounds every visual decision in UX principles and avoids generic AI aesthetics.

Toolkit for styling artifacts with a theme. These artifacts can be slides, docs, reportings, HTML landing pages, etc. There are 10 pre-set themes with colors/fonts that you can apply to any artifact that has been creating, or can generate a new theme on-the-fly.

Use this skill any time a spreadsheet file is the primary input or output. This means any task where the user wants to: open, read, edit, or fix an existing .xlsx, .xlsm, .csv, or .tsv file (e.g., adding columns, computing formulas, formatting, charting, cleaning messy data); create a new spreadsheet from scratch or from other data sources; or convert between tabular file formats. Trigger especially when the user references a spreadsheet file by name or path — even casually (like \"the xlsx in my downloads\") — and wants something done to it or produced from it. Also trigger for cleaning or restructuring messy tabular data files (malformed rows, misplaced headers, junk data) into proper spreadsheets. The deliverable must be a spreadsheet file. Do NOT trigger when the primary deliverable is a Word document, HTML report, standalone Python script, database pipeline, or Google Sheets API integration, even if tabular data is involved.

Draft release notes from merged PRs, propose a semver bump, and emit a copy-pasteable `gh release create` command. Use when preparing a tagged GitHub release.

Production-ready CI/CD configurations for Playwright — GitHub Actions, GitLab CI, CircleCI, Azure DevOps, Jenkins, Docker, parallel sharding, reporting, code coverage, and global setup/teardown.

Automates browser interactions for testing and validating your own web applications using playwright-cli. Use when you need terminal-first browser control for navigation, form filling, screenshots, tracing, bound browser sessions, debugging, or generating Playwright test code. Only use against applications you own or have explicit authorization to test.

Battle-tested Playwright patterns for writing and debugging reliable E2E, API, component, visual, accessibility, and security tests. Use when you need locator strategy, assertions, fixtures, network mocking, auth flows, trace debugging, or framework recipes for React, Next.js, Vue, and Angular. TypeScript and JavaScript.

Step-by-step migration guides for moving to Playwright from Cypress or Selenium/WebDriver — command mappings, architecture changes, and incremental adoption strategies.

Page Object Model patterns for Playwright — when to use POM, how to structure page objects, and when fixtures or helpers are a better fit.

Battle-tested Playwright patterns for writing, debugging, and scaling reliable test suites. Use when you need guidance for E2E, API, component, visual, accessibility, or security testing, plus CI/CD, CLI automation, page objects, and migration from Cypress or Selenium. TypeScript and JavaScript.

Surfaces relevant instincts during work. Use when starting a task to check if any learned behaviors apply.

Maintains awareness across sessions. Spawns observer agent on start, loads context, notifies of evolution opportunities.

Use when reviewing code for security vulnerabilities, implementing authentication/authorization, handling user input, or discussing web application security. Covers OWASP Top 10:2025, ASVS 5.0, LLM Top 10 (2025), and Agentic AI security (2026).

Create style-driven slide images strictly with the Image 2 model, assemble those images into image-only PPTX decks, and manage reusable visual style libraries from documents or visual references. Use when the user asks for a "PPT Skill", "风格驱动 PPT", "提炼风格做 PPT", "调用某个风格做 PPT", "图片版 PPT", "保存 PPT 风格", "列出 PPT 风格", "文档生成 PPT", "文章生成 PPT", "把文档做成演示文稿", or wants to extract, save, reuse, and apply visual style keywords specifically for visual slide/image deck creation.

한국 정부·공공기관 지원사업(창업지원, 사업화 자금, 입주공간, R&D, 바우처, 경진대회) 전수조사 및 프로젝트 적합성 판정 스킬. K-Startup·기업마당(bizinfo)·NIPA·KOCCA·SMTECH 공고를 크롤링해 현재 작업 폴더의 프로젝트(아이템) 프로필에 맞는 사업을 "즉시 지원 가능 / 요건 충족 시 / 변형하면 가능" 3단계로 분류하고 마감일·자격요건을 원문 검증해 보고서를 만든다. 사용자가 "지원사업 찾아줘", "정부지원", "창업지원 사업", "입주공간/사업화 자금 알아봐", "공모전/경진대회 조사", "우리 아이템에 맞는 지원사업", "K-Startup/기업마당 조사" 등을 요청하면 반드시 이 스킬을 사용한다. 이전에 조사한 적이 있는 프로젝트에서 "재조사", "새로 나온 지원사업 있나", "지난번 이후 뭐 올라왔나"를 물으면 diff 모드(증분 재조사)로 이 스킬을 사용한다. 특정 사이트를 지목하지 않아도 지원사업·보조금·정부과제 탐색 의도가 보이면 트리거된다. 단, 이미 운영 중인 소상공인·가게·점포·자영업자의 지원(소상공인 지원금, 정책자금 대출, 가게 시설개선, 소상공인24, 폐업·재기 지원)은 이 스킬이 아니라 sole-search 스킬을 사용한다. 신호가 섞이면(예: ''온라인 셀러 지원금'') 어느 쪽인지 한 번 묻는다. 사용자 신분보다 요청 목적이 우선이다 — 가게 사장이라도 신규 아이템 창업지원·R&D를 찾으면 ir-search. 한국 지원사업 전용.

Analyzes Rails applications and generates comprehensive upgrade reports with breaking changes, deprecations, and step-by-step migration guides for Rails 2.3 through 8.1. Use when upgrading Rails applications, planning multi-hop upgrades, or querying version-specific changes. Based on FastRuby.io methodology and "The Complete Guide to Upgrade Rails" ebook.

Clean up after (or abandon) a Rails upgrade. Drop NextRails.next? and NextRails.current? branches and retire dual-boot scaffolding (Gemfile.next, Gemfile.next.lock, conditional Gemfile groups), keeping either the next or the current version. Trigger when the user says they are done with the upgrade, want to clean up dual-boot, want to drop NextRails branches, want to finish the upgrade, want to abandon or revert the upgrade attempt, want to roll back to the current Rails version, or want to pause this upgrade hop. Based on FastRuby.io's "Finishing an Upgrade" methodology, extended with an abandon/pause path.

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Document-driven OSpec workflow for initialization, change/goal routing, validation, archiving, and durable project knowledge.

Create or advance a lightweight OSpec change using the classic fast workflow.

Create or advance a full OSpec goal using the current document, task graph, worker, review, and evidence workflow.

Browser automation for the user's Chrome browser. Use for browser tasks that require the user's cookies, logged-in sessions, existing tabs, extensions, or remote authenticated sites.

Platform-neutral guidance for using Open Browser Use, the open-source Chrome automation stack for AI agents. Use when an agent needs to install, verify, troubleshoot, or operate Open Browser Use through its browser extension, native CLI, JavaScript SDK, Python SDK, Go SDK, or Browser Use style JSON-RPC methods; use for tasks involving real Chrome tabs, user tab claiming, CDP commands, downloads, file choosers, clipboard helpers, or session cleanup.

Read, search, send, and manage emails via Gmail API. Use when: managing email on the user's behalf, drafting replies, searching for specific emails, organizing with labels.

View, create, update, and delete Google Calendar events. Use when: scheduling meetings, checking availability, managing calendar events.

Search, read, upload, and share files in Google Drive

Read, write, and manage Google Sheets spreadsheets

Search, read, create, and manage Notion pages and databases

Create and manage scheduled tasks with cron, interval, or one-time execution

Search messages, manage channels, reactions, pins, and users in Slack

Browse the web, take screenshots, interact with pages, fill forms. Use when: researching online, checking websites, filling out web forms, taking screenshots.

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Annotated matrices for single-cell genomics. Stores X with obs/var metadata, layers, embeddings (obsm/varm), graphs (obsp/varp), uns. Use for .h5ad/.zarr I/O, concatenation, scverse integration. For analysis use scanpy; for probabilistic models use scvi-tools.

GRN inference from expression via GRNBoost2 (gradient boosting) or GENIE3 (Random Forest). Load matrix, filter by TFs, infer TF-target-importance links, save network. Dask-parallelized to single-cell scale. Core SCENIC component.

Query ARCHS4 REST API for uniformly processed RNA-seq expression, tissue patterns, co-expression across 1M+ human/mouse samples. Retrieve z-scores, co-expressed genes, samples by metadata, HDF5 matrices. For variant population genetics use gnomad-database; for pathway enrichment use gget-genomic-databases (Enrichr).

Annotate bacterial and archaeal genomes and plasmids with Bakta's Prodigal/HMM/diamond pipeline. Identifies CDS, ncRNA, tRNA, rRNA, tmRNA, sORFs, CRISPR arrays, oriC/oriV/oriT, and gaps against a curated UniRef-derived database. Produces NCBI-compatible GFF3, GenBank, EMBL, JSON, FASTA, TSV, and a circular genome plot. Use Prokka for legacy pipelines or non-bacterial kingdoms; PGAP for NCBI GenBank submission.

CLI for VCF/BCF: filter, merge, annotate, query, normalize, compute stats. Core post-variant-calling: quality filtering, multi-sample merging, rsID annotation, genotype extraction. Samtools companion in HTSlib. Use GATK for complex indel realignment during calling; use VCFtools for population genetics stats.

Genomic interval ops on BED/BAM/GFF/VCF. Find overlaps, merge intervals, compute coverage, extract FASTA, find nearest features. Core for ChIP-seq peak annotation, region filtering, genome arithmetic. Use tabix for indexed single-region queries; use deeptools for normalized bigWig coverage.

Molecular biology toolkit: sequence manipulation, FASTA/GenBank/PDB I/O, NCBI Entrez, BLAST automation, pairwise/MSA alignment, Bio.PDB, phylogenetic trees. Use for batch processing, custom pipelines, format conversion, PubMed/GenBank queries. For quick gene lookups use gget; for multi-service REST APIs use bioservices.

Biopython sequence analysis: parse FASTA/FASTQ/GenBank/GFF (SeqIO), NCBI Entrez (esearch/efetch/elink), remote/local BLAST, pairwise/MSA alignment (PairwiseAligner, MUSCLE/ClustalW), phylogenetic trees (Phylo). Use for gene family studies, phylogenomics, comparative genomics, NCBI pipelines. For PCR/restriction/cloning use biopython-molecular-biology; for SAM/BAM use pysam.

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Guide to interpreting BUSCO completeness statuses: why Duplicated BUSCOs count as complete, parsing output files, computing/comparing completeness across proteomes/genomes, common counting mistakes. Use when running BUSCO QC, comparing assemblies, or reporting completeness. See also: prokka-genome-annotation for annotation workflows feeding BUSCO.

Fast short-read DNA aligner for WGS/WES/ChIP-seq. 2× faster BWA-MEM successor; outputs SAM/BAM with read group headers for GATK. Primary plus supplementary records for chimeric reads. Use STAR for RNA-seq splice-aware alignment; Bowtie2 is a comparable alternative.

Cancer genomics (TCGA et al.) via cBioPortal REST API. Retrieve somatic mutations, CNAs, expression, clinical data (survival/stage/treatment) across thousands of studies. Use for TMB, oncoprints, survival analysis. For population frequencies use gnomad-database; for drug-gene interactions use opentargets-database.

DL cell/nucleus segmentation for fluorescence and brightfield microscopy. Pre-trained models (cyto3, nuclei, tissuenet) and a generalist flow-based algorithm segment cells without retraining. Outputs label masks for morphology and tracking. Use scikit-image watershed for rule-based; Cellpose when DL generalization across staining is needed.

Automated scRNA-seq cell type annotation via pre-trained logistic regression. 45+ models: immune, gut, lung, brain, fetal, cancer microenvironments. Input normalized AnnData; outputs per-cell labels, majority-vote cluster labels, confidence scores. Use for fast, reference-backed annotation without manual marker inspection.

Query CELLxGENE Census (61M+ cells). Search by cell type/tissue/disease/organism; get AnnData, stream out-of-core, train PyTorch models. For your own data use scanpy; for annotated data use anndata.

Query the ClinPGx (formerly PharmGKB) REST API plus the CPIC PostgREST companion API for pharmacogenomic clinical annotations, CPIC/DPWG dosing guidelines, gene-drug pairs, variant-drug associations, FDA/EMA drug labels, and PGx pathways. Two-host architecture: api.clinpgx.org for annotation records, api.cpicpgx.org for genotype→recommendation lookups. No auth. For germline pathogenicity use clinvar-database; for somatic cancer PGx use cosmic-database or opentargets-database; for drug bioactivity use chembl-database-bioactivity.

Query NCBI ClinVar via E-utilities for variant clinical significance, pathogenicity, disease associations. Search by gene/rsID/condition/review status; returns ClinSig, submitter data, conditions, HGVS. For GWAS use gwas-database; for variant consequence prediction use Ensembl VEP.

Query COSMIC for cancer somatic mutations, gene census, mutational signatures, drug resistance variants. REST API v3.1 supports gene/sample/variant queries; free registration. For germline use clinvar-database; for drug-target data use opentargets-database or chembl-database-bioactivity.

Query NCBI dbSNP for SNP records by rsID, gene, or region via E-utilities and Variation Services REST API. Retrieve alleles, MAF, variant class (SNV/indel/MNV), clinical links, cross-DB IDs (ClinVar, dbVar, 1000G). Free; 3 req/sec (10 with key). For clinical pathogenicity use clinvar-database; for population frequencies use gnomad-database.

NGS CLI for ChIP/RNA/ATAC-seq. BAM→bigWig with RPGC/CPM/RPKM, sample correlation/PCA, heatmaps/profiles around features, fingerprints. For alignment use STAR/BWA; for peak calling use MACS2.