Claude Code Skills · page 91

Astronomical computations via Astropy. Use when: user asks about celestial coordinates, FITS files, or cosmological calculations. NOT for: telescope control or real-time observation planning.

Create, search, and manage Bear notes via grizzly CLI.

Performs bioinformatics analyses including pathway enrichment, gene ontology analysis, protein-protein interaction networks, multi-omics integration, and biological sequence database querying; trigger when users discuss gene sets, biological pathways, functional annotation, or omics data integration.

Bioinformatics operations via Biopython. Use when: user asks about DNA/protein sequences, BLAST, or PDB structures. NOT for: clinical genomics or variant calling pipelines.

Comprehensive molecular biology toolkit. Use for sequence manipulation, file parsing (FASTA/GenBank/PDB), phylogenetics, and programmatic NCBI/PubMed access (Bio.Entrez). Best for batch processing, custom bioinformatics pipelines, BLAST automation. For quick lookups use gget; for multi-service integration use bioservices.

Search bioRxiv biology preprints with natural language queries. Semantic search powered by Valyu.

Performs biostatistical analyses specialized for clinical and biomedical research including survival analysis, Kaplan-Meier estimation, Cox proportional hazards regression, longitudinal data modeling, and diagnostic test evaluation; trigger when users discuss clinical outcomes, survival curves, or biomedical study statistics.

Monitor blogs and RSS/Atom feeds for updates using the blogwatcher CLI.

BluOS CLI (blu) for discovery, playback, grouping, and volume.

Use when you need to send or manage iMessages via BlueBubbles (recommended iMessage integration). Calls go through the generic message tool with channel="bluebubbles".

You MUST use this before any creative work - creating features, building components, adding functionality, or modifying behavior. Explores user intent, requirements and design before implementation.

Capture frames or clips from RTSP/ONVIF cameras.

US Census Bureau data via API. Use when: user asks about US demographics, population, housing, or economic data by geography. NOT for: non-US data or real-time statistics.

Query ChEMBL bioactive molecules and drug discovery data. Search compounds by structure/properties, retrieve bioactivity data (IC50, Ki), find inhibitors, perform SAR studies, for medicinal chemistry.

Query the ChEMBL REST API for drug-target interactions, bioactivity data, ADMET properties, and approved drug information. Use when the user needs drug mechanism of action, binding affinity data, target information, or pharmacokinetic properties. NOT for basic compound lookup (use pubchem-compound), NOT for gene-disease associations (use open-targets), NOT for protein 3D structures (use pdb-structure).

Computational chemistry tools including molecular structure, chemical reactions, thermodynamics, spectroscopy analysis, and cheminformatics. Use when user works with chemical formulas, molecular structures, reaction balancing, thermodynamic calculations, or chemical databases (PubChem, ChemSpider). Triggers on "chemical structure", "molecular weight", "balance equation", "reaction", "thermodynamics", "spectroscopy", "SMILES", "PubChem", "chemical formula", "stoichiometry".

# Chemistry & Drug Discovery

Analyze citation networks, compute bibliometric indicators, and identify research fronts. Use when: user asks about citation patterns, h-index, co-authorship networks, research trends, or bibliometric analysis. NOT for: literature searching (use literature-search) or writing papers (use paper-writing).

Comprehensive citation management for academic research. Search Google Scholar and PubMed for papers, extract accurate metadata, validate citations, and generate properly formatted BibTeX entries. This skill should be used when you need to find papers, verify citation information, convert DOIs to BibTeX, or ensure reference accuracy in scientific writing.

Use the ClawHub CLI to search, install, update, and publish agent skills from clawhub.com. Use when you need to fetch new skills on the fly, sync installed skills to latest or a specific version, or publish new/updated skill folders with the npm-installed clawhub CLI.

Designs and analyzes clinical trials including sample size calculation, randomization schemes, endpoint selection, CONSORT reporting, and interim analysis planning; trigger when users ask about RCTs, Phase I-IV trials, or clinical study design.

Search ClinicalTrials.gov with natural language queries. Find clinical trials, enrollment, and outcomes using Valyu semantic search.

# Clinical Research

Query ClinicalTrials.gov via API v2. Search trials by condition, drug, location, status, or phase. Retrieve trial details by NCT ID, export data, for clinical research and patient matching.

Query NCBI ClinVar for variant clinical significance. Search by gene/position, interpret pathogenicity classifications, access via E-utilities API or FTP, annotate VCFs, for genomic medicine.

Execute scientific Python code for computation, data analysis, simulation, and verification. Use when: (1) running statistical analyses, (2) numerical computation, (3) data processing pipelines, (4) verifying calculations, (5) running simulations. NOT for: literature search (use literature-search), writing papers (use paper-writing), or non-computational tasks.

Scientific programming best practices including reproducible research, computational notebooks, version control for research, data management, HPC/parallel computing, and research software engineering. Use when user needs help with research code organization, reproducibility, scientific Python/R workflows, or computational infrastructure. Triggers on "reproducible research", "research code", "scientific computing", "HPC", "parallel computing", "Jupyter", "notebook", "data management plan", "research software", "code review for science".

Delegate coding tasks to Codex, Claude Code, or Pi agents via background process. Use when: (1) building/creating new features or apps, (2) reviewing PRs (spawn in temp dir), (3) refactoring large codebases, (4) iterative coding that needs file exploration. NOT for: simple one-liner fixes (just edit), reading code (use read tool), thread-bound ACP harness requests in chat (for example spawn/run Codex or Claude Code in a Discord thread; use sessions_spawn with runtime:"acp"), or any work in ~/clawd workspace (never spawn agents here). Claude Code: use --print --permission-mode bypassPermissions (no PTY). Codex/Pi/OpenCode: pty:true required.

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Spatial and temporal convergence analysis with Richardson extrapolation and Grid Convergence Index (GCI) for solution verification

Access Copernicus Climate Data Store (CDS) for ERA5 reanalysis, climate projections, and satellite observations. Use when: (1) retrieving historical weather/climate data, (2) downloading ERA5 reanalysis fields, (3) querying climate projections (CMIP), (4) getting satellite-derived climate variables. NOT for: real-time weather forecasts (use weather APIs), ocean biology (use Copernicus Marine), air quality (use CAMS).

Applies cognitive science frameworks for creative thinking to CS and AI research ideation. Use when seeking genuinely novel research directions by leveraging combinatorial creativity, analogical reasoning, constraint manipulation, and other empirically grounded creative strategies.

Academic metadata search via CrossRef API. Use when: user needs DOI resolution, citation counts, journal metadata, or publisher info. NOT for: full-text access or downloading papers.

Scientific data analysis including data cleaning, exploratory data analysis (EDA), statistical testing, regression, and reporting. Uses Python with pandas, scipy, statsmodels, scikit-learn. Use when user asks to analyze data, clean a dataset, run statistics, do EDA, fit a model, or process CSV/Excel files. Triggers on "analyze this data", "clean my dataset", "run regression", "EDA", "descriptive statistics", "data processing", "correlation analysis".

Extract numerical data from scientific figure images using Claude vision + OpenCV calibration. Supports 26+ plot types including bar charts, scatter plots, forest plots, Kaplan-Meier curves, box plots, and more.

Perform statistical tests, hypothesis testing, correlation analysis, and multiple testing corrections using scipy and statsmodels. Works with ANY LLM provider (GPT, Gemini, Claude, etc.).

Transform, clean, reshape, and preprocess data using pandas and numpy. Works with ANY LLM provider (GPT, Gemini, Claude, etc.).

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Create publication-quality plots and visualizations using matplotlib and seaborn. Works with ANY LLM provider (GPT, Gemini, Claude, etc.).

Computer science bibliography via DBLP API. Use when: user asks about CS publications, author publication lists, or venue (conference/journal) metadata. NOT for: non-CS publications or citation counts.

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Execute autonomous multi-step deep research on any topic. Use when the user asks for comprehensive research, literature reviews, competitive analysis, topic deep-dives, or wants to understand a complex subject from multiple angles. Triggers on "deep research", "research on", "investigate", "literature review", "comprehensive analysis", "what do we know about", "summarize research on".

Discord ops via the message tool (channel=discord).

Use this skill whenever the user wants to create, read, edit, or manipulate Word documents (.docx files). Triggers include: any mention of 'Word doc', 'word document', '.docx', or requests to produce professional documents with formatting like tables of contents, headings, page numbers, or letterheads. Also use when extracting or reorganizing content from .docx files, inserting or replacing images in documents, performing find-and-replace in Word files, working with tracked changes or comments, or converting content into a polished Word document. If the user asks for a 'report', 'memo', 'letter', 'template', or similar deliverable as a Word or .docx file, use this skill. Do NOT use for PDFs, spreadsheets, Google Docs, or general coding tasks unrelated to document generation.

Orchestrates a full drug discovery workflow from target identification through lead optimization. Use when searching for drug candidates against a biological target, evaluating compound libraries, or optimizing hits for drug-likeness. NOT for pure protein structure analysis or single-compound lookups.

End-to-end drug discovery platform combining ChEMBL compounds, DrugBank, targets, and FDA labels. Natural language powered by Valyu.

Supports drug discovery workflows including target identification, virtual screening, ADMET prediction, lead optimization, pharmacokinetics modeling, and drug repurposing analyses; trigger when users discuss drug targets, compound libraries, medicinal chemistry, or pharmaceutical development.

Economic analysis including econometrics, causal inference, time series economics, game theory, welfare analysis, and economic modeling. Use when user works with economic data, regression analysis, instrumental variables, difference-in-differences, RDD, panel data, or economic theory. Triggers on "econometrics", "regression", "causal inference", "instrumental variable", "difference-in-differences", "panel data", "game theory", "supply demand", "GDP", "inflation", "economic model".

Supports education research including pedagogical method evaluation, learning analytics, assessment design, curriculum development analysis, and educational technology evaluation; trigger when users discuss teaching effectiveness, learning outcomes, educational interventions, or student performance data.

Control Eight Sleep pods (status, temperature, alarms, schedules).

Analyzes energy systems including renewable energy resource assessment, power grid modeling, battery storage optimization, energy efficiency evaluation, and techno-economic analysis of energy technologies; trigger when users discuss solar, wind, grid integration, energy storage, or power system design.

Query Ensembl genome database REST API for 250+ species. Gene lookups, sequence retrieval, variant analysis, comparative genomics, orthologs, VEP predictions, for genomic research.

Analyzes environmental and climate data including temperature trends, pollution monitoring, ecological modeling, carbon footprint assessment, and biodiversity metrics; trigger when users discuss climate change, ecosystems, pollutants, or sustainability assessments.

Performs epidemiological analyses including disease modeling (SIR/SEIR), outbreak investigation, risk factor identification, incidence/prevalence estimation, and causal inference from observational data; trigger when users discuss disease spread, public health data, or population-level health patterns.

Design scientific experiments including sample size calculation, randomization, control groups, blinding, and study protocols. Covers RCTs, quasi-experiments, factorial designs, A/B tests, survey design, and observational studies. Use when user asks to design an experiment, calculate sample size, plan a study, set up controls, or create a research protocol. Triggers on "design experiment", "sample size", "power analysis", "study design", "control group", "randomization", "A/B test", "factorial design", "survey design".

Design rigorous scientific experiments with power analysis and controls. Use when: user needs to plan an experiment, calculate sample sizes, or set up controls. NOT for: running experiments or analyzing collected data.

Perform comprehensive exploratory data analysis on scientific data files across 200+ file formats. This skill should be used when analyzing any scientific data file to understand its structure, content, quality, and characteristics. Automatically detects file type and generates detailed markdown reports with format-specific analysis, quality metrics, and downstream analysis recommendations. Covers chemistry, bioinformatics, microscopy, spectroscopy, proteomics, metabolomics, and general scientific data formats.

Verify scientific claims, political statements, and environmental assertions against evidence

Helps users discover and install agent skills when they ask questions like "how do I do X", "find a skill for X", "is there a skill that can...", or express interest in extending capabilities. This skill should be used when the user is looking for functionality that might exist as an installable skill.

A harness that makes Opus (or any Claude model) behave like Fable — it enforces seeing a task through to the end, with evidence and verification, as procedure. Use when starting a multi-step task (2+ sequential stories), long autonomous work, debugging or root-cause investigation, building render/executable artifacts (HTML, SVG, games, charts), or when the user says "fablize", "see it through", "verify as you go", "split into goals".

Image processing skill for cropping images to 50% from center and rotating them 90 degrees clockwise. This skill should be used when users request image cropping to center, image rotation, or both operations combined on image files.

Replace text in fillable PDF forms by updating form field values. This skill should be used when users need to update names, addresses, dates, or other text in PDF form fields.

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Expert EU Cyber Resilience Act (CRA) advisor for Regulation (EU) 2024/2847 — mandatory cybersecurity and vulnerability handling requirements for all products with digital elements (PDEs) sold in the EU. Use this skill for gap analysis, product classification (Default / Class I / Class II), conformity assessment route selection, CE marking, SBOM requirements, vulnerability and incident reporting to ENISA/CSIRTs, support period obligations, and manufacturer/importer/distributor duties. Trigger for EU CRA, Cyber Resilience Act, PDE compliance, Annex I requirements, SBOM EU, CE marking cybersecurity, or connected product security EU.

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Expert Vietnam Personal Data Protection Law (PDPL) compliance advisor for Law No. 91/2025/QH15 and implementing Decree 356/2025/ND-CP (effective January 1, 2026). Use this skill for gap analysis against the Vietnam PDPL, data subject rights fulfilment workflows, cross-border data transfer impact assessments, privacy notices and internal policies, breach notification procedures, sector-specific obligations (finance, AI, cloud, blockchain), and DPO qualification reviews. Trigger whenever a user mentions Vietnam data privacy, VN-PDPL, Nghị định 356, Vietnamese personal data, or cross-border transfers involving Vietnamese citizens' data.

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Compatibility entry point for opening and operating Codex Slides in Codex's in-editor Browser, including scenario selection, Design Files, brand systems, decks, and Play mode. Use when the user asks to open, launch, preview, view, play, inspect, or directly manipulate Codex Slides or a deck without leaving Codex.

Compatibility entry point for scenario-led creation, Design Files, brand systems, inspecting, revising, restyling, and exporting Codex Slides slide decks. Use when a user asks Codex to make a presentation, use project files, edit an existing deck, manage slide structure, apply brand or template rules, or export PDF/PPTX.

Diagnose and recover from Codex Slides plugin, MCP, Browser handoff, local runtime, durable run, project resume, rendering, Design Files, export, and version-contract failures. Use when a tool fails, a run stalls, a project appears stale, or Codex and the Browser disagree.